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Tirzepatide

Also known as: Mounjaro, Zepbound

Tirzepatide is a dual GIP and GLP-1 receptor agonist studied for glucose regulation in type 2 diabetes and for effects on appetite and body weight. Its long half-life supports commonly reported once-weekly use. This entry is informational and is not a recommendation to use the compound.

At a glance

CategoryGLP-1 & Incretins
Classglp1-agonist, gip-agonist, incretin, dual-agonist
Half-life120 hours (about 5 days)
Typical routesubcutaneous
Common vial strengths5 mg, 10 mg, 15 mg
StorageCommonly stored refrigerated; reconstituted solutions are typically kept cold and protected from light.

Evidence and source context

Regulatory status
FDA-approved prescription medicine in specific products and indications; product labels and availability vary by market.
Evidence status
Official prescribing information and a large human clinical evidence base.
Half-life context
The official label reports an elimination half-life of approximately five to six days after subcutaneous tirzepatide. The chart uses a single fixed value and cannot represent individual pharmacokinetics.

Primary and official sources

  1. Zepbound (tirzepatide) prescribing informationU.S. Food and Drug Administration · Official label

Sources checked July 24, 2026 by the Peptilot editorial team. Independent medical review is pending; this page is educational and is not a treatment recommendation for Tirzepatide.

Elimination curve

100%50%25%12.5%51015200days after a single dose
Simple single‑compartment elimination model ((1/2)t/t½): it ignores absorption, route, and individual variation, so treat it as a shape, not a measurement. In the Peptilot app this curve is stacked across your actual logged doses.

Full clearance milestones on the Tirzepatide half-life page.

Doing the vial math? The Tirzepatide reconstitution calculator converts mg to insulin-syringe units, free and without an account.

Questions, answered.

What is Tirzepatide?
Tirzepatide is a dual GIP and GLP-1 receptor agonist studied for glucose regulation in type 2 diabetes and for effects on appetite and body weight. Its long half-life supports commonly reported once-weekly use. This entry is informational and is not a recommendation to use the compound.
What is Tirzepatide's half-life?
Tirzepatide's elimination half-life is approximately 120 hours (about 5 days), per published pharmacokinetic data. After about five half-lives (~600 hours (about 25 days)), a single dose is roughly 97% eliminated. Individual clearance varies.
Is Tirzepatide the same as Mounjaro or Zepbound?
Mounjaro and Zepbound are brand-name medicines whose active ingredient is tirzepatide. People commonly track their prescribed brand under the tirzepatide entry.
What do people log alongside Tirzepatide?
People tracking this compound often log gastrointestinal tolerance, appetite, and body weight over time. Peptilot has one-tap logging for doses, side effects, weight, and injection sites, so patterns show up in your own record.

Educational information for people who track their protocols — not medical advice, and never a recommendation to use any compound. Always work with a qualified healthcare provider.

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