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MOTS-c

Also known as: MOTS-C

MOTS-c is a mitochondrial-derived peptide studied primarily in preclinical research on exercise capacity, metabolism, and insulin sensitivity. It is widely regarded as a research compound. This entry is informational and is not a recommendation to use the compound.

At a glance

CategoryLongevity & Mitochondrial
Classpeptide, mitochondrial-derived-peptide, research-peptide
Half-lifeabout 30 minutes
Typical routesubcutaneous
Common vial strengths10 mg
StorageLyophilized powder is commonly stored frozen or refrigerated; reconstituted solutions are typically kept refrigerated.

Elimination curve

100%50%25%12.5%3060901200minutes after a single dose
Simple single‑compartment elimination model ((1/2)t/t½): it ignores absorption, route, and individual variation, so treat it as a shape, not a measurement. In the Peptilot app this curve is stacked across your actual logged doses.

Full clearance milestones on the MOTS-c half-life page.

Doing the vial math? The MOTS-c reconstitution calculator converts mg to insulin-syringe units, free and without an account.

Questions, answered.

What is MOTS-c?
MOTS-c is a mitochondrial-derived peptide studied primarily in preclinical research on exercise capacity, metabolism, and insulin sensitivity. It is widely regarded as a research compound. This entry is informational and is not a recommendation to use the compound.
What is MOTS-c's half-life?
MOTS-c's elimination half-life is approximately about 30 minutes, per published pharmacokinetic data. After about five half-lives (~2.5 hours), a single dose is roughly 97% eliminated. Individual clearance varies.
Is MOTS-c the same as MOTS-C?
MOTS-C is another name associated with MOTS-c.
What do people log alongside MOTS-c?
People tracking this research compound often log injection-site tolerance and exercise-related observations. Peptilot has one-tap logging for doses, side effects, weight, and injection sites, so patterns show up in your own record.

Educational information for people who track their protocols — not medical advice, and never a recommendation to use any compound. Always work with a qualified healthcare provider.

Track MOTS-c with one-tap dose logs, estimated level charts, site rotation, and reminders — free for your first 3 days.

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