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Melanotan II

Also known as: Melanotan 2, MT-2, MT-II

Melanotan II is a synthetic melanocortin-receptor agonist that has been studied for its effects on skin pigmentation and is widely regarded as a research compound that is not approved for general use. Reported effects also include changes in appetite and other melanocortin-mediated responses. This entry is informational and is not a recommendation to use the compound.

At a glance

CategoryCosmetic & Other
Classpeptide, melanocortin-agonist, research-peptide
Half-life1 hour
Typical routesubcutaneous
Common vial strengths10 mg
StorageLyophilized powder is commonly stored frozen or refrigerated; reconstituted solutions are typically kept refrigerated and protected from light.

Elimination curve

100%50%25%12.5%12340hours after a single dose
Simple single‑compartment elimination model ((1/2)t/t½): it ignores absorption, route, and individual variation, so treat it as a shape, not a measurement. In the Peptilot app this curve is stacked across your actual logged doses.

Full clearance milestones on the Melanotan II half-life page.

Doing the vial math? The Melanotan II reconstitution calculator converts mg to insulin-syringe units, free and without an account.

Questions, answered.

What is Melanotan II?
Melanotan II is a synthetic melanocortin-receptor agonist that has been studied for its effects on skin pigmentation and is widely regarded as a research compound that is not approved for general use. Reported effects also include changes in appetite and other melanocortin-mediated responses. This entry is informational and is not a recommendation to use the compound.
What is Melanotan II's half-life?
Melanotan II's elimination half-life is approximately 1 hour, per published pharmacokinetic data. After about five half-lives (~5 hours), a single dose is roughly 97% eliminated. Individual clearance varies.
Is Melanotan II the same as Melanotan 2 or MT-2 or MT-II?
Melanotan 2 and MT-2 and MT-II are other names associated with Melanotan II.
What do people log alongside Melanotan II?
People tracking this research compound often log skin or pigmentation observations, nausea, and flushing. Peptilot has one-tap logging for doses, side effects, weight, and injection sites, so patterns show up in your own record.

Educational information for people who track their protocols — not medical advice, and never a recommendation to use any compound. Always work with a qualified healthcare provider.

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