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PT-141 (Bremelanotide) half-life

PT-141 (Bremelanotide) has an elimination half-life of approximately 2.7 hours. Here is what that means for how long a single dose stays in your system.

100%50%25%12.5%2.75.48.1110hours after a single dose
Simple single‑compartment elimination model ((1/2)t/t½): it ignores absorption, route, and individual variation, so treat it as a shape, not a measurement. In the Peptilot app this curve is stacked across your actual logged doses.

Clearance milestones

MilestoneTime after a single dose
50% eliminated~2.7 h
75% eliminated~5.4 h
90% eliminated~9 h
~97% eliminated (≈5 half-lives)~14 h

About PT-141 (Bremelanotide)

PT-141 (Bremelanotide) is a melanocortin-receptor agonist that has been studied in the context of sexual function and has an approved indication for certain patients in that area. It is typically described as being used on an as-needed basis. This entry is informational and is not a recommendation to use the compound.

See the full PT-141 (Bremelanotide) compound page or the PT-141 (Bremelanotide) reconstitution calculator, or compare against other compounds on the half-life overview.

Questions, answered.

What is PT-141 (Bremelanotide)'s half-life?
PT-141 (Bremelanotide)'s elimination half-life is approximately 2.7 hours, based on published pharmacokinetic data. That means about half of a dose is eliminated in that time, half of the remainder in the next interval, and so on.
How long does PT-141 (Bremelanotide) stay in your system?
Using the ~5-half-lives rule of thumb, a single dose of PT-141 (Bremelanotide) is roughly 97% eliminated after ~14 h. Actual clearance varies with dose history, route, and individual metabolism — treat this as an educational estimate, not a measurement.
Do levels build up with repeated doses?
Yes — if a new dose lands before the previous one is eliminated, the remainders stack. With consistent dosing, estimated levels reach steady state after roughly four to five half-lives. Peptilot's Levels feature stacks this exact curve across your logged doses so you can see the estimate for your own history.

Educational information for people who track their protocols — not medical advice, and never a recommendation to use any compound. Always work with a qualified healthcare provider.

Peptilot charts your estimated PT-141 (Bremelanotide) levels from the doses you actually log — in any browser, free for your first 3 days.

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