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MK-677 (Ibutamoren)

Also known as: MK-677, Ibutamoren, MK-0677, Nutrobal

MK-677 (Ibutamoren) is an orally active growth-hormone secretagogue and ghrelin-receptor agonist studied for its effect on growth-hormone and IGF-1 levels. Note: it is a non-peptide small molecule, not a peptide, despite often being grouped with growth-hormone peptides. This entry is informational and is not a recommendation to use the compound.

At a glance

CategoryGrowth Hormone Secretagogues
Classnon-peptide, small-molecule, growth-hormone-secretagogue, orally-active
Half-life24 hours
Typical routeoral
StorageAs an orally active compound it is commonly stored cool, dry, and away from light.

Elimination curve

100%50%25%12.5%12340days after a single dose
Simple single‑compartment elimination model ((1/2)t/t½): it ignores absorption, route, and individual variation, so treat it as a shape, not a measurement. In the Peptilot app this curve is stacked across your actual logged doses.

Full clearance milestones on the MK-677 (Ibutamoren) half-life page.

Questions, answered.

What is MK-677 (Ibutamoren)?
MK-677 (Ibutamoren) is an orally active growth-hormone secretagogue and ghrelin-receptor agonist studied for its effect on growth-hormone and IGF-1 levels. Note: it is a non-peptide small molecule, not a peptide, despite often being grouped with growth-hormone peptides. This entry is informational and is not a recommendation to use the compound.
What is MK-677 (Ibutamoren)'s half-life?
MK-677 (Ibutamoren)'s elimination half-life is approximately 24 hours, per published pharmacokinetic data. After about five half-lives (~120 hours (about 5 days)), a single dose is roughly 97% eliminated. Individual clearance varies.
Is MK-677 (Ibutamoren) the same as MK-677 or Ibutamoren or MK-0677 or Nutrobal?
MK-677 and Ibutamoren and MK-0677 and Nutrobal are other names associated with MK-677 (Ibutamoren).
What do people log alongside MK-677 (Ibutamoren)?
People tracking this compound often log appetite, water retention, sleep, and related observations. Peptilot has one-tap logging for doses, side effects, weight, and injection sites, so patterns show up in your own record.

Educational information for people who track their protocols — not medical advice, and never a recommendation to use any compound. Always work with a qualified healthcare provider.

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